Dosing
CrCl > 80: 150 mg/kg initially, then 6 doses of 65 mg/kg q 12 h.
Important side effects
Neurologic sx of all kinds(cerebellar ataxia, coma, dementia, headache, lethargy, movement disorder, muscle weakness, paresthesia, psychiatric findings, seizures, vertigo).
Important drug interactions
Rants and Screeds
Pearls
Paralyzes the worm and relieves gi obstruction. So warn the patient they will pass whole worms. Ick.