Nifurtimox
Dosing
CrCl > 80: 8 - 10 mg/kg/d in 3 - 4 doses.
CrCl 80-50:
CrCl 50-10:
CrCl < 10:
Hemodialysis:
Peritoneal dialysis:
Important side effects
GI upset, all manner of CNS ( cns excitation, depression, fatigue, headache, memory impairment, paresthesias or peripheral neuropathy, tremors, vertigo or ataxia, weakness, sleep disorders).